Review article: the histological assessment of disease activity in ulcerative colitis.
Fiche publication
Date publication
octobre 2015
Journal
Alimentary pharmacology & therapeutics
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BOULAGNON-ROMBI Camille, Pr PEYRIN-BIROULET Laurent
Tous les auteurs :
Marchal Bressenot A, Riddell RH, Boulagnon-Rombi C, Reinisch W, Danese S, Schreiber S, Peyrin-Biroulet L
Lien Pubmed
Résumé
In patients with ulcerative colitis (UC), mucosal healing has emerged as a major therapeutic goal, and is usually assessed endoscopically. Histological healing does not correlate very well with endoscopic mucosal healing in UC and persistent histological inflammation might be a better predictor of future clinical relapse than the endoscopic appearance alone.
Mots clés
Biopsy, Colitis, Ulcerative, pathology, Disease Progression, Histological Techniques, Humans, Male, Middle Aged, Rectum, pathology, Recurrence, Research Design, Wound Healing
Référence
Aliment. Pharmacol. Ther.. 2015 Oct;42(8):957-67