Targeting DNA repair in combination with radiotherapy in pancreatic cancer: A systematic review of preclinical studies.
Fiche publication
Date publication
juillet 2020
Journal
Critical reviews in oncology/hematology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr NOEL Georges, Dr BURCKEL Hélène, Mme NICOL Anaïs
Tous les auteurs :
Waissi W, Paix A, Nicol A, Noël G, Burckel H
Lien Pubmed
Résumé
Current research that combines radiation with targeted therapy may dramatically improve prognosis of pancreatic ductal adenocarcinoma (PDAC). We investigated preclinical outcomes of DNA repair inhibitor targeted therapy associated with radiotherapy.
Mots clés
DNA repair, Inhibitors, Pancreatic cancer, Radiosensitization, Radiotherapy, Targeted therapy
Référence
Crit. Rev. Oncol. Hematol.. 2020 Jul 11;153:103060