Respective stemness and chondrogenic potential of mesenchymal stem cells isolated from human bone marrow, synovial membrane, and synovial fluid.
Fiche publication
Date publication
juillet 2020
Journal
Stem cell research & therapy
Auteurs
Membres identifiés du Cancéropôle Est :
Pr GILLET Pierre, Pr MAINARD Didier
Tous les auteurs :
Neybecker P, Henrionnet C, Pape E, Grossin L, Mainard D, Galois L, Loeuille D, Gillet P, Pinzano A
Lien Pubmed
Résumé
MSCs isolated from bone marrow (BM-MSCs) have well-established chondrogenic potential, but MSCs derived from the synovial membrane (SM-MSCs) and synovial fluid (SF-MSCs) are thought to possess superior chondrogenicity. This study aimed to compare the in vitro immunophenotype and trilineage and chondrogenic potential of BM-MSCs to SM-MSCs and SF-MSCs.
Mots clés
Bone marrow, Cartilage engineering, Chondrogenic differentiation, Growth factors, Mesenchymal stromal stem cells, Synovial fluid, Synovial membrane
Référence
Stem Cell Res Ther. 2020 Jul 25;11(1):316