Short-Term Effects of Air Pollution on Coronary Events in Strasbourg, France-Importance of Seasonal Variations.
Fiche publication
Date publication
août 2020
Journal
Medical sciences (Basel, Switzerland)
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MEYER Nicolas, Dr MOITRY Marie, Pr SAULEAU Erik-André
Tous les auteurs :
Vaudrey B, Mielcarek M, Sauleau E, Meyer N, Marchandot B, Moitry M, Robellet P, Reeb T, Jesel L, Ohlmann P, Bourdrel T, Morel O
Lien Pubmed
Résumé
The aim of this study, is to investigate the effects of a short-term exposure to air pollutants, as assessed by Nitrogen dioxide (NO), Particulate Matter PM and PM concentrations, on coronary event onsets in Strasbourg, France. An observational, analytical, retrospective, epidemiological study was conducted in Strasbourg between 1 January 2012 and 31 December 2014. Higher daily coronary events rates were evidenced when NO concentrations were measured above 40 µg/m (1.258 (95% CI 1.142-1.374) vs. 1.110 (95% CI 1.033-1.186); = 0.015). The NO concentration was higher than 30 µg/m for 677 days (61.8%). Higher daily coronary events rates were evidenced when NO concentrations were measured above 30 µg/m (1.208 (95% CI 1.128-1.289) vs. 1.067 (95% CI 0.961-1.172) = 0.009). A marked seasonality of NO, PM, and PM concentrations characterized by an increase during winter and a decrease during the summer could be established. The seasonality of coronary events was evidenced simultaneously. After adjustments were made to account for the time and the month, no independent impact of NO, PM or PM on daily coronary events could be demonstrated.
Mots clés
NO2, PM10, PM2.5, acute coronary syndrome, air pollution, seasonality
Référence
Med Sci (Basel). 2020 Aug 7;8(3):