Pre-operative growth differentiation factor 15 as a novel biomarker of acute kidney injury after cardiac bypass surgery.
Fiche publication
Date publication
octobre 2015
Journal
International journal of cardiology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr VERGELY Catherine
Tous les auteurs :
Guenancia C, Kahli A, Laurent G, Hachet O, Malapert G, Grosjean S, Girard C, Vergely C, Bouchot O
Lien Pubmed
Résumé
Pre-operative GDF-15 plasma levels significantly improve the prognostic value of the EuroSCORE for mortality after cardiac surgery. However, despite the strong correlation between GDF-15 and renal function, no data are available regarding the potential interest of pre-operative GDF-15 levels to improve the prediction of acute kidney injury (AKI) after cardiac artery bypass graft (CABG) surgery.
Mots clés
Acute Kidney Injury, diagnosis, Aged, Biomarkers, blood, Coronary Artery Bypass, adverse effects, Female, Growth Differentiation Factor 15, blood, Humans, Immunoenzyme Techniques, Male, Middle Aged, Preoperative Period, Prospective Studies, Regression Analysis, Risk Factors
Référence
Int. J. Cardiol.. 2015 Oct;197:66-71