Identification of TGFβ signatures in six murine models mimicking different osteoarthritis clinical phenotypes.
Fiche publication
Date publication
juillet 2020
Journal
Osteoarthritis and cartilage
Auteurs
Membres identifiés du Cancéropôle Est :
Pr JOUZEAU Jean-Yves
Tous les auteurs :
Maumus M, Noel D, Ea HK, Moulin D, Ruiz M, Hay E, Houard X, Cleret D, Cohen-Solal M, Jacques C, Jouzeau JY, Lafage-Proust MH, Reboul P, Sellam J, Vinatier C, Rannou F, Jorgensen C, Guicheux J, Berenbaum F
Lien Pubmed
Résumé
TGFβ is a key player in cartilage homeostasis and OA pathology. However, few data are available on the role of TGFβ signalling in the different OA phenotypes. Here, we analysed the TGFβ pathway by transcriptomic analysis in six mouse models of OA.
Mots clés
murine model, osteoarthritis, signature, transcriptomic
Référence
Osteoarthr. Cartil.. 2020 Jul 10;: