Renal Programming by Transient Postnatal Overfeeding: The Role of Senescence Pathways.

Fiche publication


Date publication

janvier 2020

Journal

Frontiers in physiology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr VERGELY Catherine


Tous les auteurs :
Juvet C, Siddeek B, Yzydorczyk C, Vergely C, Nardou K, Armengaud JB, Benahmed M, Simeoni U, Cachat F, Chehade H

Résumé

Early nutrition influences the risk of chronic kidney diseases (CKDs) development in adulthood. Mechanisms underlying the early programming of altered renal function remain incompletely understood. This study aims at characterizing the role of cell senescence pathways in early programming of CKD after transient postnatal overfeeding.

Mots clés

chronic kidney disease, developmental origins of health and disease, kidney, overnutrition, postnatal overfeeding, programming

Référence

Front Physiol. 2020 ;11:511