Targeting the gut layers in Crohn's disease: mucosal or transmural healing?
Fiche publication
Date publication
juin 2020
Journal
Expert review of gastroenterology & hepatology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr PEYRIN-BIROULET Laurent
Tous les auteurs :
Zacharopoulou E, Craviotto V, Fiorino G, Furfaro F, Zilli A, Gilardi D, Peyrin-Biroulet L, Danese S, Allocca M
Lien Pubmed
Résumé
Although the landmark of Crohn's Disease (CD) is the transmural inflammation, mucosal healing (MH), which is assessed by colonoscopy, is currently the gold standard of CD management. Transmural healing (TH) is a new concept evaluated by cross-sectional imaging (CSI) techniques, such as bowel ultrasound (US), computed tomography enterography (CTE) and magnetic resonance enterography (MRE). Little is known about the clinical significance of persisting mural disease and the predictive value of complete TH.
Mots clés
Crohn’s disease, bowel ultrasound, computed tomography enterography, magnetic resonance enterography, mucosal healing, outcomes, transmural healing
Référence
Expert Rev Gastroenterol Hepatol. 2020 Jun 9;: