Does type of immunosupression influence the course of Covid-19 infection?
Fiche publication
Date publication
juin 2020
Journal
The Journal of infection
Auteurs
Membres identifiés du Cancéropôle Est :
Dr MANSI Laura, Dr DAGUINDAU Etienne
Tous les auteurs :
Razanamahery J, Soumagne T, Humbert S, Brunel AS, Lepiller Q, Daguindau E, Mansi L, Chirouze C, Bouiller K
Lien Pubmed
Résumé
Coronavirus disease 19 (Covid-19) is a new emerging virus responsible for pandemic and death. High blood pressure, diabetes, obesity have been described as poor prognosis factors. Few data have been reported in patient with immunocompromised status (solid tumor, hematological malignancy, rheumatoid conditions or organ transplant). We evaluated the characteristics of patients, including the outcome, with immunodepression hospitalized in Besancon University hospital (East of France). We wanted to identify if a type of immunosupression influences the course of Covid-19. In a cohort of 80 patients with immunosupression (42 solid tumors, 20 hematological malignancy and 18 non neoplastic immunosupression), poor outcomes (Intensive care unit hospitalization and or deaths) was frequent (38%) and tended to be more frequent in patients with hematological malignancy.
Mots clés
Covid-19, cancer, immunosupression, poor outcomes
Référence
J. Infect.. 2020 Jun 3;: