Intra-arterial hepatic beads loaded with irinotecan (DEBIRI) with mFOLFOX6 in unresectable liver metastases from colorectal cancer: a Phase 2 study.

Fiche publication


Date publication

juin 2020

Journal

British journal of cancer

Auteurs

Membres identifiés du Cancéropôle Est :
Dr JOUVE Jean-Louis, Pr LEPAGE Côme


Tous les auteurs :
Pernot S, Pellerin O, Artru P, Montérymard C, Smith D, Raoul JL, De La Fouchardière C, Dahan L, Guimbaud R, Sefrioui D, Jouve JL, Lepage C, Tougeron D, Taieb J,

Résumé

Chemo-embolisation with drug-eluting beads loaded with irinotecan (DEBIRI) increased survival as compared with intravenous irinotecan in chemorefractory patients with liver-dominant metastases from colorectal cancer (LMCRC). First-line DEBIRI with systemic chemotherapy may increase survival and secondary resection.

Référence

Br. J. Cancer. 2020 Jun 8;: