Two Diagnostic Criteria of Optical Spectroscopy for Bladder Tumor Detection: Clinical Study using 5-ALA induced fluorescence and Mathematical Modeling.
Fiche publication
Date publication
mai 2020
Journal
Photodiagnosis and photodynamic therapy
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BLONDEL Walter, Pr DAUL Christian, Dr AMOUROUX Marine
Tous les auteurs :
Kalyagina N, Loshchenov M, Amouroux M, Daul C, Kudashev B, Blondel W, Loschenov V
Lien Pubmed
Résumé
The study proposes to improve bladder cancer diagnosis by (i) photodynamic diagnosis (PDD) using red-light excitation (632.8 nm) of 5-ALA induced-protoporphyrin IX in 9 patients' bladder associated to the analysis of two types of signals to improve the diagnostic accuracy, and (ii) numerical modeling of scattering coefficient for providing biological explanations of the results obtained.
Mots clés
bladder cancer, diffuse reflectance, fluorescence, laser signal, optical spectroscopy, photodynamic diagnosis, scattering
Référence
Photodiagnosis Photodyn Ther. 2020 May 20;:101829