Sentinel European Node Trial (SENT): 3-year results of sentinel node biopsy in oral cancer.

Fiche publication


Date publication

décembre 2015

Journal

European journal of cancer (Oxford, England : 1990)

Auteurs

Membres identifiés du Cancéropôle Est :
Pr DOLIVET Gilles, Dr LEROUX Agnès, Dr MASTRONICOLA Romina


Tous les auteurs :
Schilling C, Stoeckli SJ, Haerle SK, Broglie MA, Huber GF, Sorensen JA, Bakholdt V, Krogdahl A, von Buchwald C, Bilde A, Sebbesen LR, Odell E, Gurney B, O'Doherty M, de Bree R, Bloemena E, Flach GB, Villarreal PM, Fresno Forcelledo MF, Junquera Gutiérrez LM, Amézaga JA, Barbier L, Santamaría-Zuazua J, Moreira A, Jacome M, Vigili MG, Rahimi S, Tartaglione G, Lawson G, Nollevaux MC, Grandi C, Donner D, Bragantini E, Dequanter D, Lothaire P, Poli T, Silini EM, Sesenna E, Dolivet G, Mastronicola R, Leroux A, Sassoon I, Sloan P, McGurk M

Résumé

Optimum management of the N0 neck is unresolved in oral cancer. Sentinel node biopsy (SNB) can reliably detect microscopic lymph node metastasis. The object of this study was to establish whether the technique was both reliable in staging the N0 neck and a safe oncological procedure in patients with early-stage oral squamous cell carcinoma.

Mots clés

Adult, Aged, Aged, 80 and over, Carcinoma, Squamous Cell, mortality, Chemoradiotherapy, Adjuvant, Disease-Free Survival, Europe, False Negative Reactions, Female, Head and Neck Neoplasms, mortality, Humans, Kaplan-Meier Estimate, Lymph Nodes, pathology, Lymphatic Metastasis, Male, Middle Aged, Mouth Neoplasms, mortality, Neck Dissection, Neoplasm Micrometastasis, Neoplasm Staging, Predictive Value of Tests, Proportional Hazards Models, Prospective Studies, Radiotherapy, Adjuvant, Risk Factors, Sentinel Lymph Node Biopsy, adverse effects, Time Factors, Treatment Outcome

Référence

Eur. J. Cancer. 2015 Dec;51(18):2777-84