Evolving therapeutic goals in Crohn's disease management.
Fiche publication
Date publication
mars 2020
Journal
United European gastroenterology journal
Auteurs
Membres identifiés du Cancéropôle Est :
Pr PEYRIN-BIROULET Laurent
Tous les auteurs :
Chateau T, Peyrin-Biroulet L
Lien Pubmed
Résumé
The main objectives in Crohn's disease are to avoid disease complications and preserve the patient's quality of life. Early disease control and close monitoring with specific targets to reach might be the only way to change the disease course. In two decades, we have moved from clinical response to full remission (clinical and endoscopic remission) requiring a tight monitoring of both symptoms and objective signs of inflammation. This review summarizes the concepts of tight control and treat-to-target and their potential for disease modification.
Mots clés
Crohn's disease, Tight control, treat-to-target
Référence
United European Gastroenterol J. 2020 Mar;8(2):133-139