Vibration of effects from diverse inclusion/exclusion criteria and analytical choices: 9216 different ways to perform an indirect comparison meta-analysis.
Fiche publication
Date publication
septembre 2019
Journal
BMC medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Dr HAMMAS Karima
Tous les auteurs :
Palpacuer C, Hammas K, Duprez R, Laviolle B, Ioannidis JPA, Naudet F
Lien Pubmed
Résumé
Different methodological choices such as inclusion/exclusion criteria and analytical models can yield different results and inferences when meta-analyses are performed. We explored the range of such differences, using several methodological choices for indirect comparison meta-analyses to compare nalmefene and naltrexone in the reduction of alcohol consumption as a case study.
Mots clés
Alcoholism, Meta-analysis, Nalmefene, Naltrexone, Vibration of effect
Référence
BMC Med. 2019 09 16;17(1):174