Evaluating the clinical effectiveness and safety of various HER2-targeted regimens after prior taxane/trastuzumab in patients with previously treated, unresectable, or metastatic HER2-positive breast cancer: a systematic review and network meta-analysis.

Fiche publication


Date publication

février 2020

Journal

Breast cancer research and treatment

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PIVOT Xavier


Tous les auteurs :
Paracha N, Reyes A, Diéras V, Krop I, Pivot X, Urruticoechea A

Résumé

In the absence of head-to-head trial data, network meta-analysis (NMA) was used to compare trastuzumab emtansine (T-DM1) with other approved treatments for previously treated patients with unresectable or metastatic HER2-positive breast cancer (BC).

Mots clés

Capecitabine, Lapatinib, Locally advanced, Neratinib, Pertuzumab, Trastuzumab emtansine

Référence

Breast Cancer Res. Treat.. 2020 Feb 25;: