Carbapenem-Susceptible OXA-23-Producing Proteus mirabilis in the French Community.
Fiche publication
Date publication
juin 2019
Journal
Antimicrobial agents and chemotherapy
Auteurs
Membres identifiés du Cancéropôle Est :
Pr HOCQUET Didier
Tous les auteurs :
Potron A, Hocquet D, Triponney P, Plésiat P, Bertrand X, Valot B
Lien Pubmed
Résumé
Nineteen isolates producing the carbapenemase OXA-23 were recovered over a 2-year period in 19 French hospitalized patients, of whom 12 had community onset infections. The isolates exhibited a slightly reduced susceptibility to carbapenems. Whole-genome analysis revealed that all 19 isolates formed a cluster compared to 149 other isolates. Because of its susceptibility to carbapenems, this clone may be misidentified as a penicillinase producer while it constitutes a reservoir of the OXA-23-encoding gene in the community.
Mots clés
OXA-23, Proteus mirabilis , carbapenemase, clonality, spread
Référence
Antimicrob. Agents Chemother.. 2019 06;63(6):