Motion compensated generalized reconstruction for free-breathing dynamic contrast-enhanced MRI.
Fiche publication
Date publication
mars 2011
Journal
Magnetic resonance in medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Pr FELBLINGER Jacques, Dr VUISSOZ Pierre-André
Tous les auteurs :
Filipovic M, Vuissoz PA, Codreanu A, Claudon M, Felblinger J
Lien Pubmed
Résumé
The analysis of abdominal and thoracic dynamic contrast-enhanced MRI is often impaired by artifacts and misregistration caused by physiological motion. Breath-hold is too short to cover long acquisitions. A novel multipurpose reconstruction technique, entitled dynamic contrast-enhanced generalized reconstruction by inversion of coupled systems, is presented. It performs respiratory motion compensation in terms of both motion artefact correction and registration. It comprises motion modeling and contrast-change modeling. The method feeds on physiological signals and x-f space properties of dynamic series to invert a coupled system of linear equations. The unknowns solved for represent the parameters for a linear nonrigid motion model and the parameters for a linear contrast-change model based on B-splines. Performance is demonstrated on myocardial perfusion imaging, on six simulated data sets and six clinical exams. The main purpose consists in removing motion-induced errors from time-intensity curves, thus improving curve analysis and postprocessing in general. This method alleviates postprocessing difficulties in dynamic contrast-enhanced MRI and opens new possibilities for dynamic contrast-enhanced MRI analysis.
Mots clés
Algorithms, Artifacts, Contrast Media, Heart, anatomy & histology, Humans, Image Enhancement, methods, Image Interpretation, Computer-Assisted, methods, Magnetic Resonance Angiography, Meglumine, Motion, Myocardial Perfusion Imaging, Organometallic Compounds, Reproducibility of Results, Respiratory Mechanics, Sensitivity and Specificity
Référence
Magn Reson Med. 2011 Mar;65(3):812-22