Head-to-head comparison between digital and analog PET of human and phantom images when optimized for maximizing the signal-to-noise ratio from small lesions.

Fiche publication

Date publication

février 2020


EJNMMI physics


Membres identifiés du Cancéropôle Est :
Pr KARCHER Gilles, Pr MARIE Pierre-Yves, Pr OLIVIER Pierre, Pr VERGER Antoine

Tous les auteurs :
Salvadori J, Odille F, Verger A, Olivier P, Karcher G, Marie PY, Imbert L


Routine PET exams are increasingly performed with reduced injected activities, leading to the use of different image reconstruction parameters than the NEMA parameters, in order to prevent from any deleterious decrease in signal-to-noise ratio (SNR) and thus, in lesion detectability. This study aimed to provide a global head-to-head comparison between digital (Vereos, Philips®) and analog (Ingenuity TF, Philips®) PET cameras of the trade-off between SNR and contrast through a wide-ranging number of reconstruction iterations, and with a further reconstruction optimization based on the SNR of small lesions.

Mots clés

Digital PET, Image quality, Optimization, Time-of-flight


EJNMMI Phys. 2020 Feb 21;7(1):11