Both preoperative alpha and calcium channel blockade impact intraoperative hemodynamic stability similarly in the management of pheochromocytoma.
Fiche publication
Date publication
décembre 2014
Journal
Surgery
Auteurs
Membres identifiés du Cancéropôle Est :
Dr NGUYEN-THI Phi Linh , Pr GERMAIN Adeline
Tous les auteurs :
Brunaud L, Boutami M, Nguyen-Thi PL, Finnerty B, Germain A, Weryha G, Fahey TJ, Mirallie E, Bresler L, Zarnegar R
Lien Pubmed
Résumé
Alpha-blockade is the standard management preoperatively to prevent intraoperative hemodynamic instability (IHD) during resection of a pheochromocytoma. Calcium channel blockers also have been shown to lessen the risk of IHD. We aim to determine differences between these classes of antihypertensive agents in minimizing IHD.
Mots clés
Adrenal Gland Neoplasms, drug therapy, Adrenalectomy, methods, Adrenergic alpha-Antagonists, therapeutic use, Adult, Aged, Antihypertensive Agents, therapeutic use, Calcium Channel Blockers, therapeutic use, Cohort Studies, Databases, Factual, Female, Follow-Up Studies, Hemodynamics, drug effects, Humans, Intraoperative Complications, prevention & control, Male, Middle Aged, Monitoring, Intraoperative, methods, Pheochromocytoma, drug therapy, Preoperative Care, Reference Values, Retrospective Studies, Risk Assessment, Treatment Outcome
Référence
Surgery. 2014 Dec;156(6):1410-7; discussion1417-8