Childhood maltreatment and clinical severity of treatment-resistant depression in a French cohort of outpatients (FACE-DR): One-year follow-up.
Fiche publication
Date publication
janvier 2020
Journal
Depression and anxiety
Auteurs
Membres identifiés du Cancéropôle Est :
Pr HAFFEN Emmanuel
Tous les auteurs :
Yrondi A, Aouizerate B, Bennabi D, Richieri R, D'Amato T, Bellivier F, Bougerol T, Horn M, Camus V, Courtet P, Doumy O, Genty JB, Holtzmann J, Lancon C, Leboyer M, Llorca PM, Maruani J, Moirand R, Molière F, Samalin L, Schmitt L, Stephan F, Turecki G, Vaiva G, Walter M, Petrucci J, , Haffen E, El-Hage W
Lien Pubmed
Résumé
Childhood maltreatment is associated with major depressive disorder (MDD). It not only increases the risk of lifetime MDD, but it also aggravates its course. Among depressed patients, 20-30% of them experience treatment-resistance depression (TRD). We aimed to assess the association between childhood maltreatment, severity of depression in a unipolar TRD sample, and patient outcomes after one-year of follow-up.
Mots clés
antidepressant response, childhood abuse, childhood neglect, childhood trauma, depressive disorders, treatment-resistant depression
Référence
Depress Anxiety. 2020 Jan 30;: