[Other therapeutic strategies].

Fiche publication


Date publication

mars 2016

Journal

Presse medicale (Paris, France : 1983)

Auteurs

Membres identifiés du Cancéropôle Est :
Pr HAFFEN Emmanuel


Tous les auteurs :
Saba G, Nieto I, Bation R, Allaïli N, Bennabi D, Moliere F, Richieri R, Holtzmann J, Bubrovszky M, Camus V, Charpeaud T, Courtet P, Courvoisier P, Haesebaert F, Doumy O, El-Hage W, Garnier M, d'Amato T, Bougerol T, Lançon C, Haffen E, Llorca PM, Vaiva G, Bellivier F, Leboyer M, Aouizerate B

Résumé

Non-selective and irreversible MAOI have become as third or fourth-line strategy for the management of treatment-resistant depression. Non-selective and irreversible MAOI requires careful monitoring of drug interactions and dietary restrictions. Nutritional supplements such as omega-3 have been found to produce beneficial effects in the management of treatment-resistant depression when administered in combination with the ongoing antidepressant treatment. The glutamate antagonist ketamine has been found to produce beneficial effects in the management of treatment-resistant depression while administered alone. Dopamine and/or norepinephrine agonists, such as methylphenidate, modafinil or pramipexole, have been found to produce beneficial effects in the management of treatment-resistant depression when administered in combination with the ongoing antidepressant treatment.

Mots clés

Adrenergic alpha-Agonists, therapeutic use, Antidepressive Agents, pharmacokinetics, Central Nervous System Stimulants, therapeutic use, Depressive Disorder, drug therapy, Dietary Supplements, Dopamine Agonists, therapeutic use, Double-Blind Method, Drug Interactions, Drug Resistance, Drug Therapy, Combination, Excitatory Amino Acid Antagonists, therapeutic use, Fatty Acids, Omega-3, therapeutic use, Folic Acid, therapeutic use, Food-Drug Interactions, Humans, Ketamine, therapeutic use, Monoamine Oxidase Inhibitors, pharmacokinetics, Randomized Controlled Trials as Topic, S-Adenosylmethionine, therapeutic use

Référence

Presse Med. 2016 Mar;45(3):350-9