[Trisomy 21 and breast cancer: A genetic abnormality which protects against breast cancer?].
Fiche publication
Date publication
avril 2016
Journal
Gynecologie, obstetrique & fertilite
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MATHELIN Carole, Dr TOMASETTO Catherine
Tous les auteurs :
Martel-Billard C, Cordier C, Tomasetto C, Jégu J, Mathelin C
Lien Pubmed
Résumé
Trisomy 21 (T21) is the most common chromosomal abnormality and one of the main causes of intellectual disability. The tumor profile of T21 patients is characterized by the low frequency of solid tumors including breast cancer.
Mots clés
Adolescent, Adult, Aged, Breast Neoplasms, epidemiology, Child, Chromosomes, Human, Pair 21, Down Syndrome, genetics, Female, Humans, Middle Aged
Référence
Gynecol Obstet Fertil. 2016 Apr;44(4):211-7