FDG PET/CT in Type I Glycogen Storage Disease.
Fiche publication
Date publication
avril 2016
Journal
Clinical nuclear medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MARIE Pierre-Yves, Pr VERGER Antoine, Dr CLAUDIN Marine
Tous les auteurs :
Manca C, Claudin M, Belle A, Marie PY, Verger A
Lien Pubmed
Résumé
Type I glycogen storage disease (GSD) is a rare autosomal recessive disorder caused by glucose-6-phosphatase deficiency. We report herein the particular pattern provided by FDG PET imaging in a 33-year-old patient with type Ib GSD. PET images yielded evidence of a pulmonary infectious focus as well as of: (1) a dramatically enlarged liver leading to a high global FDG uptake, (2) increased bone marrow activity, (3) splenomegalia leading to a high global spleen uptake, (4) a diffuse enhancement in muscle FDG uptake.
Mots clés
Adult, Glycogen Storage Disease Type I, diagnostic imaging, Humans, Male, Multimodal Imaging, Positron-Emission Tomography, Tomography, X-Ray Computed
Référence
Clin Nucl Med. 2016 Apr;41(4):e200-1