Fatal acute respiratory distress by Toxoplasma gondii in a toxoplasma seronegative liver transplant recipient.
Fiche publication
Date publication
avril 2016
Journal
The new microbiologica
Auteurs
Membres identifiés du Cancéropôle Est :
Pr DI MARTINO Vincent, Pr HEYD Bruno
Tous les auteurs :
Miltgen G, Paillot J, Vanlemmens C, Di Martino V, Heyd B, Millon L, Bellanger AP
Lien Pubmed
Résumé
The risk of Toxoplasma gondii infection in solid organ transplant recipients is well known but mainly after heart transplantation. We discuss a case of acute respiratory distress caused by Toxoplasma gondii on Day 32 after liver transplantation. The reported case, which is extremely rare, emphasizes how direct examination and Quantitative Polymerase Chain Reaction (QPCR) in broncholaveolar lavage help to diagnose the infection. Given Trimethoprim/Sulfamethoxazole toxicity, systematic prescription of Toxoplasma gondii chemoprophylaxis is not commonly approved in liver transplantation.
Mots clés
Fatal Outcome, Female, Humans, Immunocompromised Host, Liver Transplantation, adverse effects, Lung Diseases, Parasitic, etiology, Middle Aged, Tissue Donors, Toxoplasmosis, pathology
Référence
New Microbiol.. 2016 Apr;39(2):160-2