Atherosclerotic renal artery stenosis in the post-CORAL era part 1: the renal penumbra concept and next-generation functional diagnostic imaging.
Fiche publication
Date publication
avril 2016
Journal
Journal of the American Society of Hypertension : JASH
Auteurs
Membres identifiés du Cancéropôle Est :
Pr ROSSIGNOL Patrick
Tous les auteurs :
Sag AA, Inal I, Okcuoglu J, Rossignol P, Ortiz A, Afsar B, Sos TA, Kanbay M
Lien Pubmed
Résumé
After three neutral trials in which renal artery stenting failed to improve renal function or reduce cardiovascular and renal events, the controversy surrounding diagnosis and treatment of atherosclerotic renal artery stenosis and renovascular hypertension has led to paradigm shifts in the diagnostic algorithm. Noninvasive determination of earlier events (cortex hypoxia and renal artery hemodynamic changes) will supersede late sequelae (calcific stenosis, renal cortical thinning). Therefore, this review proposes the concept of renal penumbra in defining at-risk ischemic renal parenchyma. The complex field of functional renal magnetic resonance imaging will be reviewed succinctly in a clinician-directed fashion.
Mots clés
Atherosclerosis, complications, Datasets as Topic, Diagnostic Imaging, instrumentation, Endovascular Procedures, methods, Humans, Hypertension, Renovascular, diagnostic imaging, Ischemia, diagnostic imaging, Kidney, diagnostic imaging, Magnetic Resonance Imaging, methods, Parenchymal Tissue, diagnostic imaging, Randomized Controlled Trials as Topic, Renal Artery Obstruction, diagnostic imaging, Stents
Référence
J Am Soc Hypertens. 2016 Apr;10(4):360-7