Tumefactive inflammatory leukoencephalopathy in cocaine users: Report of three cases.
Fiche publication
Date publication
novembre 2019
Journal
Multiple sclerosis and related disorders
Auteurs
Membres identifiés du Cancéropôle Est :
Dr LHERMITTE Benoît, Pr DE SEZE Jérôme
Tous les auteurs :
Pessini LM, Kremer S, Auger C, Castilló J, Pottecher J, de Sèze J, Lhermitte B, Maciag E, Rovira A
Lien Pubmed
Résumé
Cocaine is the most common illicit stimulant drug used in Europe, and it can potentially affect the central nervous system due to a direct effect, or by means of additive drugs. Levamisole has been increasingly used as an additive drug since it extends the stimulating effects of cocaine. This has led to an increase in the detection of levamisole adverse reactions, including levamisole-induced multifocal inflammatory leukoencephalopathy (MIL), a potentially lethal monophasic cerebral demyelinating disease.
Mots clés
Cocaine, Levamisole, MS differential diagnosis, Multifocal inflammatory leukoencephalopathy, Tumefactive
Référence
Mult Scler Relat Disord. 2019 Nov 4;38:101496