CHIPOFIL: A pilot study assessing the feasibility of HIPEC without extracorporeal circuit.

Fiche publication

Date publication

septembre 2019


Pleura and peritoneum


Membres identifiés du Cancéropôle Est :
Pr BINQUET Christine, Dr FACY Olivier, Pr ORTEGA DEBALLON Pablo, Pr RAT Patrick

Tous les auteurs :
Ortega-Deballon P, Facy O, Binquet C, Delroeux D, Rat P


Heated intraperitoneal chemotherapy (HIPEC) is currently performed using an external circuit including a heating device and a pump. Available devices have several drawbacks in terms of costs, technique (flow surges due to blocked tubes) and staff safety, hindering a wider use. In a previous preclinical study conducted in animals, we placed a heating wire within the abdomen to achieve and maintain hyperthermia. Our results showed this technique is safe and effective. The present pilot study was conceived as the first use of such a device in humans, aiming to confirm its safety and efficacy.

Mots clés

HIPEC, heated intraperitoneal chemotherapy, heating wire, hyperthermia, peritoneal carcinomatosis


Pleura Peritoneum. 2019 Sep 1;4(3):20190008