CHIPOFIL: A pilot study assessing the feasibility of HIPEC without extracorporeal circuit.
Fiche publication
Date publication
septembre 2019
Journal
Pleura and peritoneum
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BINQUET Christine, Dr FACY Olivier, Pr ORTEGA DEBALLON Pablo, Pr RAT Patrick
Tous les auteurs :
Ortega-Deballon P, Facy O, Binquet C, Delroeux D, Rat P
Lien Pubmed
Résumé
Heated intraperitoneal chemotherapy (HIPEC) is currently performed using an external circuit including a heating device and a pump. Available devices have several drawbacks in terms of costs, technique (flow surges due to blocked tubes) and staff safety, hindering a wider use. In a previous preclinical study conducted in animals, we placed a heating wire within the abdomen to achieve and maintain hyperthermia. Our results showed this technique is safe and effective. The present pilot study was conceived as the first use of such a device in humans, aiming to confirm its safety and efficacy.
Mots clés
HIPEC, heated intraperitoneal chemotherapy, heating wire, hyperthermia, peritoneal carcinomatosis
Référence
Pleura Peritoneum. 2019 Sep 1;4(3):20190008