Pregnancy outcomes in prenatally diagnosed 47, XXX and 47, XYY syndromes: a 30-year French, retrospective, multicentre study.
Fiche publication
Date publication
juin 2016
Journal
Prenatal diagnosis
Auteurs
Membres identifiés du Cancéropôle Est :
Dr COLLONGE-RAME Marie-Agnès
Tous les auteurs :
Gruchy N, Blondeel E, Le Meur N, Joly-Hélas G, Chambon P, Till M, Herbaux M, Vigouroux-Castera A, Coussement A, Lespinasse J, Amblard F, Jimenez Pocquet M, Lebel-Roy C, Carré-Pigeon F, Flori E, Mugneret F, Jaillard S, Yardin C, Harbuz R, Collonge-Rame MA, Vago P, Valduga M, Leporrier N, Vialard F
Lien Pubmed
Résumé
Sex chromosome aneuploidies are frequently detected fortuitously in a prenatal diagnosis. Most cases of 47, XXX and 47, XYY syndromes are diagnosed in this context, and parents are thus faced with an unexpected situation. The objective of the present study was to characterize a French cohort of prenatally diagnosed cases of 47, XXX and 47, XYY and to evaluate the termination of pregnancy (TOP) rate before and after France's implementation of multidisciplinary centres for prenatal diagnosis in 1997.
Mots clés
Abortion, Induced, trends, Abortion, Spontaneous, epidemiology, Adult, Amniocentesis, Chorionic Villi Sampling, Chromosomes, Human, X, Cohort Studies, Female, Fetal Death, France, epidemiology, Humans, Maternal Age, Pregnancy, Pregnancy Outcome, epidemiology, Prenatal Diagnosis, Retrospective Studies, Sex Chromosome Aberrations, Sex Chromosome Disorders, diagnosis, Sex Chromosome Disorders of Sex Development, diagnosis, Trisomy, diagnosis, XYY Karyotype, diagnosis
Référence
Prenat. Diagn.. 2016 Jun;36(6):523-9