Ki67 expression in bronchial preneoplastic lesions and carcinoma in situ defined according to the new 1999 WHO/IASLC criteria: a preliminary study.
Fiche publication
Date publication
janvier 2004
Journal
Histopathology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MASCAUX Céline
Tous les auteurs :
Meert AP, Feoli F, Martin B, Verdebout JM, Mascaux C, Verhest A, Ninane V, Sculier JP
Lien Pubmed
Résumé
The World Health Organization classification of bronchial intraepithelial neoplastic lesions has been shown to be reproducible. However little is known about its biological value. The aim of this study was to assess the proliferative activity of mild (MiD), moderate (MoD), severe (SD) dysplasia and carcinoma in situ (CIS) by the expression of Ki67 on biopsy specimens obtained during fluorescence bronchoscopy.
Mots clés
Biopsy, Bronchi, metabolism, Bronchoscopy, Carcinoma in Situ, classification, Cell Count, Humans, Immunoenzyme Techniques, Ki-67 Antigen, metabolism, Lung Neoplasms, classification, Precancerous Conditions, classification, World Health Organization
Référence
Histopathology. 2004 Jan;44(1):47-53