The prognostic effect of single and multiple cancer-related somatic mutations in resected non-small-cell lung cancer.
Fiche publication
Date publication
septembre 2018
Journal
Lung cancer (Amsterdam, Netherlands)
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MASCAUX Céline
Tous les auteurs :
Jao K, Tomasini P, Kamel-Reid S, Korpanty GJ, Mascaux C, Sakashita S, Labbé C, Leighl NB, Liu G, Feld R, Bradbury PA, Hwang DM, Pintilie M, Tsao MS, Shepherd FA
Lien Pubmed
Résumé
Somatic mutations are becoming increasingly important biomarkers for treatment selection and outcome in patients with non-small-cell lung cancer (NSCLC). The role of multiple somatic mutations in early-stage NSCLC is unclear.
Mots clés
EGFR, KRAS, non-small-cell lung cancer, Prognostic, TP53
Référence
Lung Cancer. 2018 09;123:22-29