Serum and peritoneal exudate concentrations after high doses of β-lactams in critically ill patients with severe intra-abdominal infections: an observational prospective study.
Fiche publication
Date publication
octobre 2019
Journal
The Journal of antimicrobial chemotherapy
Auteurs
Membres identifiés du Cancéropôle Est :
Pr THILLY Nathalie, Pr GERMAIN Adeline
Tous les auteurs :
Leon L, Guerci P, Pape E, Thilly N, Luc A, Germain A, Butin-Druoton AL, Losser MR, Birckener J, Scala-Bertola J, Novy E
Lien Pubmed
Résumé
Critically ill patients with severe intra-abdominal infections (IAIs) requiring surgery may undergo several pharmacokinetic (PK) alterations that can lead to β-lactam underdosage.
Référence
J. Antimicrob. Chemother.. 2019 Oct 10;: