Histone H1 variant-specific lysine methylation by G9a/KMT1C and Glp1/KMT1D.
Fiche publication
Date publication
mars 2010
Journal
Epigenetics & chromatin
Auteurs
Membres identifiés du Cancéropôle Est :
Dr DAUJAT Sylvain
Tous les auteurs :
Weiss T, Hergeth S, Zeissler U, Izzo A, Tropberger P, Zee BM, Dundr M, Garcia BA, Daujat S, Schneider R
Lien Pubmed
Résumé
The linker histone H1 has a key role in establishing and maintaining higher order chromatin structure and in regulating gene expression. Mammals express up to 11 different H1 variants, with H1.2 and H1.4 being the predominant ones in most somatic cells. Like core histones, H1 has high levels of covalent modifications; however, the full set of modifications and their biological role are largely unknown.
Référence
Epigenetics Chromatin. 2010 Mar;3(1):7