Wayanin and guaijaverin, two active metabolites found in a Psidium acutangulum Mart. ex DC (syn. P. persoonii McVaugh) (Myrtaceae) antimalarial decoction from the Wayana Amerindians.

Fiche publication


Date publication

juillet 2016

Journal

Journal of ethnopharmacology

Auteurs

Membres identifiés du Cancéropôle Est :
Dr VILLA Pascal


Tous les auteurs :
Houël E, Nardella F, Jullian V, Valentin A, Vonthron-Sénécheau C, Villa P, Obrecht A, Kaiser M, Bourreau E, Odonne G, Fleury M, Bourdy G, Eparvier V, Deharo E, Stien D

Résumé

Psidium acutangulum Mart. ex DC is a small tree used by the Wayana Amerindians from the Upper-Maroni in French Guiana for the treatment of malaria.

Mots clés

Animals, Anti-Inflammatory Agents, pharmacology, Antimalarials, pharmacology, Cell Line, Cell Survival, drug effects, Cells, Cultured, Cercopithecus aethiops, Cytokines, metabolism, Flavonoids, pharmacology, French Guiana, Fruit, Humans, Indians, South American, Leukocytes, Mononuclear, drug effects, Mice, Nitric Oxide, metabolism, Plant Extracts, pharmacology, Plant Leaves, Plant Stems, Plasmodium falciparum, drug effects, Psidium, RAW 264.7 Cells, Rats, Vero Cells

Référence

J Ethnopharmacol. 2016 Jul;187:241-8