Main biomarkers associated with age-related plasma zinc decrease and copper/zinc ratio in healthy elderly from ZincAge study.

Fiche publication


Date publication

juillet 2016

Journal

European journal of nutrition

Auteurs

Membres identifiés du Cancéropôle Est :
Pr HERBEIN Georges


Tous les auteurs :
Giacconi R, Costarelli L, Piacenza F, Basso A, Rink L, Mariani E, Fulop T, Dedoussis G, Herbein G, Provinciali M, Jajte J, Lengyel I, Mocchegiani E, Malavolta M

Résumé

Zinc (Zn) plays an essential role in many biological processes including immune response. Impaired Zn status promotes immune dysfunction, and it has been associated with enhanced chronic inflammation during aging. It has been suggested that the measurement of circulating Zn by itself could not reflect the real Zn status of an individual. It is therefore necessary to identify other determinants associated with plasma Zn to better understanding how physiopathological conditions during aging may affect the concentration of this metal.

Référence

Eur J Nutr. 2016 Jul;: