The anti-fibrotic role of mast cells in the liver is mediated by HLA-G and interaction with hepatic stellate cells.
Fiche publication
Date publication
mai 2019
Journal
Cytokine
Auteurs
Membres identifiés du Cancéropôle Est :
Dr DRENOU Bernard
Tous les auteurs :
Amiot L, Vu N, Drenou B, Scrofani M, Chalin A, Devisme C, Samson M
Lien Pubmed
Résumé
We have reported a significant association between HLA-G expression or the number of hepatic mast cells and liver fibrosis. Here, we investigated the role of HLA-G and mast cells in liver fibrosis, focusing, in particular, on interactions between human mast and stellate cells.
Mots clés
Fibrosis, HLA-G, Hepatic stellate cells, Mast cells
Référence
Cytokine. 2019 May;117:50-58