Automated and efficient radiosynthesis of [(18)F]FLT using a low amount of precursor.
Fiche publication
Date publication
août 2016
Journal
Nuclear medicine and biology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BRASSE David, Pr LAQUERRIERE Patrice
Tous les auteurs :
Marchand P, Ouadi A, Pellicioli M, Schuler J, Laquerriere P, Boisson F, Brasse D
Lien Pubmed
Résumé
Since 1991 until now, many radiosyntheses of [(18)F]FLT have been published. Most of them suffer from side reactions and/or difficult purification related to the large amount of precursor necessary for the labeling step. A fully automated synthesis using only commercial and unmodified materials with a reduced amount of precursor would be desirable.
Référence
Nucl. Med. Biol.. 2016 Aug;43(8):520-7