[Hyperpigmentation].
Fiche publication
Date publication
septembre 2019
Journal
Annales de dermatologie et de venereologie
Auteurs
Membres identifiés du Cancéropôle Est :
Pr LIPSKER Dan
Tous les auteurs :
Lipsker D, Lenormand C
Lien Pubmed
Résumé
The key diagnostic tool for hyperpigmentation is histopathology, which may be accompanied by certain laboratory tests. Hyperpigmentation may result from excess melanin (hypermelanosis), cutaneous iron deposits (hemosiderosis), cutaneous carotene deposits (carotenoderma), or cutaneous deposits of a substance not normally found in the skin (dyschromia). The different types of hypermelanosis may be classified as either localised or generalised. The former generally correspond to skin tumours and may form a cutaneous expression of complex syndromes, which most notably include cardiac abnormalities, or to pigmented forms of inflammatory and/or infectious dermatoses. Diffuse hypermelanosis is frequently a sign of systemic disease, generally metabolic or endocrine disease, or else it may result from pharmaceutical therapy. Herein we review the various causes of hyperpigmentation and the corresponding therapy.
Mots clés
Adrenal Cortical Tropic Hormone, Chloasma, Couleur de la peau, Haemochromatosis, Hormone adrénocorticotropique, Hypermelanosis, Hypermélanose, Hyperpigmentation, Hémochromatose, Skin
Référence
Ann Dermatol Venereol. 2019 Sep 16;: