Advanced nanostructured medical device combining mesenchymal cells and VEGF nanoparticles for enhanced engineered tissue vascularization.
Fiche publication
Date publication
septembre 2016
Journal
Nanomedicine (London, England)
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BENKIRANE-JESSEL Nadia, Dr IDOUX-GILLET Ysia
Tous les auteurs :
Wagner Q, Offner D, Idoux-Gillet Y, Saleem I, Somavarapu S, Schwinté P, Benkirane-Jessel N, Keller L
Lien Pubmed
Résumé
Success of functional vascularized tissue repair depends on vascular support system supply and still remains challenging. Our objective was to develop a nanoactive implant enhancing endothelial cell activity, particularly for bone tissue engineering in the regenerative medicine field.
Mots clés
Animals, Bone Development, drug effects, Bone Substitutes, administration & dosage, Endothelial Cells, drug effects, Humans, Neovascularization, Pathologic, Neovascularization, Physiologic, drug effects, Prostheses and Implants, Regenerative Medicine, Tissue Engineering
Référence
Nanomedicine (Lond). 2016 Sep;11(18):2419-30