Progranulin autoantibodies in systemic sclerosis and autoimmune connective tissue disorders: A preliminary study.
Fiche publication
Date publication
septembre 2019
Journal
Immunity, inflammation and disease
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MARTIN Thierry
Tous les auteurs :
Klemm P, Assmann G, Preuss KD, Fadle N, Regitz E, Martin T, Pfreundschuh M, Thurner L
Lien Pubmed
Résumé
The present study aimed to investigate progranulin autoantibodies in systemic sclerosis and autoimmune connective tissue disorders. Progranulin is a physiologic tumor necrosis factor (TNF) antagonist. Progranulin antibodies decrease progranulin levels.
Mots clés
TNF, autoimmune connective tissue disorders, progranulin, proinflammatory autoantibody, systemic sclerosis
Référence
Immun Inflamm Dis. 2019 Sep 10;: