Realtime Tracking of the Photobleaching Trajectory During Photodynamic Therapy.
Fiche publication
Date publication
octobre 2016
Journal
IEEE transactions on bio-medical engineering
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BARBERI-HEYOB Muriel, Pr BASTOGNE Thierry, Dr FROCHOT Céline
Tous les auteurs :
Tylcz JB, Bastogne T, Bourguignon A, Frochot C, Barberi-Heyob M
Lien Pubmed
Résumé
Photodynamic therapy (PDT) is an alternative treatment for cancer that involves the administration of a photosensitizing agent, which is activated by light at a specific wavelength. This illumination causes after a sequence of photoreactions, the production of reactive oxygen species responsible for the death of the tumor cells but also the degradation of the photosensitizing agent, which then loose the fluorescence properties. The phenomenon is commonly known as photobleaching process and can be considered as a therapy efficiency indicator.
Référence
IEEE Trans Biomed Eng. 2016 Oct;: