Considerations, challenges and future of anti-TNF therapy in treating inflammatory bowel disease.

Fiche publication


Date publication

octobre 2016

Journal

Expert opinion on biological therapy

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PEYRIN-BIROULET Laurent


Tous les auteurs :
Pouillon L, Bossuyt P, Peyrin-Biroulet L

Résumé

Crohn's disease (CD) and ulcerative colitis (UC) are chronic disabling conditions. Monoclonal antibody therapy directed against tumor necrosis factor-alpha (anti-TNF) has revolutionized the care of patients with inflammatory bowel disease (IBD).

Mots clés

Adalimumab, Crohn’s disease, TNF antagonists, anti-TNF, biosimilar, certolizumab pegol, combination therapy, golimumab, inflammatory bowel disease, infliximab, personalized medicine, pharmacogenomics, tailored therapy, therapeutic drug monitoring, ulcerative colitis

Référence

Expert Opin Biol Ther. 2016 10;16(10):1277-90