Cavernous sinus thrombosis secondary to aspergillus granuloma: A case report and review of the literature.

Fiche publication


Date publication

octobre 2016

Journal

Auris, nasus, larynx

Auteurs

Membres identifiés du Cancéropôle Est :
Dr BOULAGNON-ROMBI Camille


Tous les auteurs :
Brenet E, Boulagnon-Rombi C, N'guyen Y, Litré CF

Résumé

Cavernous sinus thrombosis is a rare but serious complication of sphenoid aspergillosis. The rarity of this pathology makes its diagnostic very difficult on a clinical, biological and radiological sense. The authors present a case of cavernous sinus thrombosis with ipsilateral internal carotid artery thrombosis secondary to a non-invasive sphenoid aspergillosis in an immunocompetent host, responsible of a cavernous syndrome associated to a Claude Bernard Horner syndrome. One year after surgery, the patient is still asymptomatic without recurrence. Diagnostic modalities are detailed and several management of this pathology are compared. Surgery is essential in a diagnostic and therapeutic sense. There is no evidence of the interest of adjuvant therapies such as antibiotic and anticoagulation. Concerning the antifungal treatment, the attitude towards a non-invasive sphenoid aspergillosis in an immunocompetent host is unclear.

Mots clés

Aged, Aspergillosis, complications, Aspergillus fumigatus, Carotid Artery Thrombosis, diagnostic imaging, Cavernous Sinus Thrombosis, diagnostic imaging, Cerebral Angiography, Foreign Bodies, complications, Granuloma, Foreign-Body, complications, Horner Syndrome, etiology, Humans, Immunocompetence, Magnetic Resonance Imaging, Male, Sphenoid Sinusitis, complications

Référence

Auris Nasus Larynx. 2016 Oct;43(5):566-9