The TRANSPLANTEX initiative.
Fiche publication
Date publication
novembre 2016
Journal
Human immunology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BAHRAM Siamak, Dr CARAPITO Raphaël
Tous les auteurs :
Bahram S, Carapito R, Gourraud PA, Charron D
Lien Pubmed
Résumé
TRANSPLANTEX, a French "investment for the future" initiated consortium of leading transplant units and research laboratories across France and a number of European countries aims to unravel, through mainly high-throughput genomics (and other omics) analyses of donor and recipients, novel (a) non-HLA, histocompatibility antigens, whether inside, or outside the MHC; (b) pre/post transplantation biomarkers. This shall lead to our better understanding of the pathophysiology of (and eventually designing better therapeutics for) the graft-versus-host disease in hematopoietic cell transplants and that of chronic graft rejection after kidney transplant. Industrial developments as well as innovative teaching initiatives are also integral part of this program. The present issue of Human Immunology aims to present a first snapshot of some of the research performed by TRANPLANTEX partners.
Mots clés
Biomarkers, metabolism, Consensus, France, Graft Rejection, diagnosis, Graft vs Host Disease, diagnosis, Histocompatibility Testing, Humans, Immunosuppression, Kidney Transplantation, Registries
Référence
Hum. Immunol.. 2016 Nov;77(11):1005-1007