Interpreting Registrational Clinical Trials of Biological Therapies in Adults with Inflammatory Bowel Diseases.
Fiche publication
Date publication
novembre 2016
Journal
Inflammatory bowel diseases
Auteurs
Membres identifiés du Cancéropôle Est :
Pr PEYRIN-BIROULET Laurent
Tous les auteurs :
Ghosh S, Sandborn WJ, Colombel JF, Feagan BG, Panaccione R, Hanauer S, Schreiber S, Peyrin-Biroulet L, Vermeire S, Eichner S, Huang B, Robinson AM, Pappalardo B
Lien Pubmed
Résumé
The use of biologics to treat inflammatory bowel disease is supported by robust randomized controlled trials in both ulcerative colitis and Crohn's disease. Nonetheless, an understanding of the principles of clinical trial design is necessary to extrapolate study findings to clinical practice.
Mots clés
Adult, Biological Therapy, methods, Colitis, Ulcerative, therapy, Crohn Disease, therapy, Data Interpretation, Statistical, Humans, Randomized Controlled Trials as Topic, Research Design
Référence
Inflamm. Bowel Dis.. 2016 11;22(11):2711-2723