Cockayne syndrome: a diffusion tensor imaging and volumetric study.
Fiche publication
Date publication
novembre 2016
Journal
The British journal of radiology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MEYER Nicolas
Tous les auteurs :
Koob M, Rousseau F, Laugel V, Meyer N, Armspach JP, Girard N, Dietemann JL
Lien Pubmed
Résumé
Cockayne syndrome (CS) is a rare disorder characterized by severe brain atrophy, white matter (WM) hypomyelination and basal ganglia calcifications. This study aimed to quantify atrophy and WM abnormalities using diffusion tensor imaging (DTI) and volumetric analysis, to evaluate possible differences between CS subtypes and to determine whether DTI findings may correspond to a hypomyelinating disorder.
Mots clés
Adolescent, Adult, Anisotropy, Case-Control Studies, Child, Child, Preschool, Cockayne Syndrome, diagnostic imaging, Diffusion Tensor Imaging, methods, Female, Humans, Image Interpretation, Computer-Assisted, Imaging, Three-Dimensional, Infant, Male
Référence
Br J Radiol. 2016 Nov;89(1067):20151033