[Granulosa cell tumor of the ovary: retrospective study of 17 cases].
Fiche publication
Date publication
mai 2014
Auteurs
Membres identifiés du Cancéropôle Est :
Dr LEROUX Agnès, Pr MARCHAL Frédéric, Dr LEUFFLEN Léa
Tous les auteurs :
Rebstock LE, Leufflen L, Leroux A, Harter V, Verhaeghe JL, Marchal F
Lien Pubmed
Résumé
Granulosa cell tumors of the ovary are rare tumor of ovary, included in the sex cord-stromal tumor category, hormone secreting. Seventeen patients with adult-type granulosa cell tumor were identified between 1995 and 2012. All have received surgical treatment first at stage I. Thirty-three percent of the patients relapsed with peritoneal nodules in 68% of the cases, treated surgically and sometimes with complementary therapies, such as chemotherapy, radiotherapy, hormonal treatment. Overall survival and recurrence-free survival were 100% and 58.3%, respectively at 10 years with median time to recurrence of 6 years (4-27). These tumors have therefore a good prognosis and require long-time follow-up. Finally, the prognostic factors of recurrence identified in the literature are FIGO stage, the presence of residual tumor and tumor size.
Référence
Gynecol Obstet Fertil. 2014 May;42(5):331-3