Hints for control of infection in unique extrahepatic vertebral alveolar echinococcosis.
Fiche publication
Date publication
décembre 2016
Journal
Infection
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BLAGOSKLONOV Oleg
Tous les auteurs :
Faucher JF, Descotes-Genon C, Hoen B, Godard J, Félix S, Aubry S, Blagosklonov O, Grenouillet F, Brientini MP, Richou C, Bresson-Hadni S, Chirouze C
Lien Pubmed
Résumé
The prognosis of vertebral alveolar echinococcosis (AE) is poor. We report on the unique outcome of a patient with preexisting liver cirrhosis, in whom a diagnosis of vertebral AE was established on vertebral histopathology (D4 corporectomy in 2010 for paraplegia). Therapeutic drug monitoring of albendazole (ABZ) showed that a low dosage was appropriate. The patient recovered and ABZ withdrawal was decided in 2014, with no relapse 18 months later. In this patient, infection was purely or mainly localized in the dorsal spine, and this may have been favored by liver cirrhosis. A longer follow-up is, however, needed to confirm cure.
Référence
Infection. 2016 Dec;: