Epidermal growth factor receptor and v-Ki-ras2 Kirsten rat sarcoma viral oncogen homologue-specific amino acid substitutions are associated with different histopathological prognostic factors in resected non-small-cell lung cancer.
Fiche publication
Date publication
décembre 2016
Journal
Interactive cardiovascular and thoracic surgery
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BEAU-FALLER Michèle, Pr CHENARD Marie-Pierre, Pr FALCOZ Pierre-Emmanuel, Pr OLLAND Anne
Tous les auteurs :
Seitlinger J, Renaud S, Falcoz PE, Schaeffer M, Olland A, Reeb J, Santelmo N, Legrain M, Voegeli AC, Weingertner N, Chenard MP, Beau-Faller M, Massard G
Lien Pubmed
Résumé
Epidermal growth factor receptor (mEGFR) and v-Ki-ras2 Kirsten rat sarcoma viral oncogen homologue (mKRAS) mutations are the two main oncogenic drivers in resected non-small-cell lung cancer (NSCLC). We aimed to evaluate the correlation between histopathological prognostic factors and these mutations in resected NSCLC.
Référence
Interact Cardiovasc Thorac Surg. 2016 Dec;23(6):902-907