An usual cause of elliptocytosis.
Fiche publication
Date publication
décembre 2016
Journal
Annales de biologie clinique
Auteurs
Membres identifiés du Cancéropôle Est :
Dr LESESVE Jean-François, Pr BROSEUS Julien, Dr D'AVENI-PINEY Maud
Tous les auteurs :
Broséus J, Roth-Guépin G, D'Aveni-Piney M, Perrot A, Lesesve JF, Perrin J
Lien Pubmed
Résumé
We report a 60-year-old adult case with a normocytic normochromic regenerative anemia discovered incidentally. The objectification of elliptocytosis accompanied by splenomegaly, a collagen myelofibrosis and the presence of the mutation JAK2V617F allowed the diagnosis of primary myelofibrosis with atypical initial presentation. The causes of elliptocytoses are discussed.
Mots clés
Anemia, complications, Elliptocytosis, Hereditary, complications, Humans, Incidental Findings, Janus Kinase 2, genetics, Male, Middle Aged, Mutation, Primary Myelofibrosis, complications
Référence
Ann. Biol. Clin. (Paris). 2016 Dec;74(6):704-707