Albumin as a carrier for NO delivery: preparation, physicochemical characterization, and interaction with gold nanoparticles.
Fiche publication
Date publication
décembre 2016
Journal
Drug development and industrial pharmacy
Auteurs
Membres identifiés du Cancéropôle Est :
Dr VINCOURT Jean-Baptiste
Tous les auteurs :
Luo M, Boudier A, Pallotta A, Maincent P, Vincourt JB, Leroy P
Lien Pubmed
Résumé
Nitric oxide (NO) is a gaseous transmitter playing numerous physiological roles and characterized by a short half-life. Its binding to endogenous thiols increases its stability, facilitating its storage and transport. The purpose of this study was to investigate the nitrosated serum albumin (SA-SNO) and to provide a reference for its easy preparation for further use in in vitro studies.
Référence
Drug Dev Ind Pharm. 2016 Dec;42(12):1928-1937